Prenatal omega-3 supplementation could protect from house dust mite allergy


There has been a large increase in allergic diseases over the last 30 years, and it has occurred too rapidly (within one to two generations) to be a result of genetic changes in the population, so it is likely to be related to environmental changes. The period of increase in allergic diseases has coincided with a substantial shift in dietary intake of fatty acids to favour omega 6 over omega 3, and this has led to think that the change in dietary fatty acid balance may be linked to the increased prevalence of childhood allergies.

Dust mites and their waste products are one of the most common causes of not seasonal allergy. Dust mites are tiny bugs (they measure only about one-quarter to one-third of a millimeter) that live in almost every household in the world (excepting Antarctica), and they feed mainly on dead skin from pets and humans (an adult person may shed up to 1.5 grams of skin in a day, and this is enough to feed one million dust mites). The waste products of dust mites, not the mites themselves, are what cause allergic reactions; and throughout its short lifetime, a single dust mite may produce as much as 200 times its body weight in waste products (which contain a protein that is an allergen).

Kids born to mothers who had taken high doses of fish oil during pregnancy seem to be less likely to have some types of allergies. In particular, at six years of age there are less children with allergy to house dust mite among those born to mothers who took fish oil during pregnancy than among those born to mothers who didn’t take omega-3 suplementation. Prenatal omega-3 rich fish oil supplementation could have a protective effect on house dust mite allergy.


Best KP, Sullivan T, Palmer D, et al. Prenatal Fish Oil Supplementation and Allergy: 6-Year Follow-up of a Randomized Controlled Trial. Pediatrics. 2016 Jun;137(6).

Palmer DJ, Sullivan T, Gold MS, et al. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants’ allergies in first year of life: Randomised controlled trial. BMJ. 2012;344:e184

Asthma and Allergy Foundation of America. Dust Mite Allergy. Disponible en:

nutrigenomica y omega-3

Nutrigenomics and omega-3 fatty acids

Each cell in the human body contains about 25,000 to 35,000 genes. Genes carry the information that determines our traits; each gene has specific instructions for making proteins: [...]