Omega-3 in the prevention of migraine attacks


Migraine reduces the quality of life, is related with professional absenteeism and is associated with other health problems. Several medicines are used in the prevention of headache attacks in people suffering from migraine, but people with chronic daily headache often achieve only transient relief with conventional medical management.

There are also non-pharmacological treatments (acupuncture, relaxation techniques, biofeedback, psychotherapy, and dietary therapy). In relation to dietary therapy, it has been observed that omega-3 fatty acids (present in large amounts in salmon, tuna, mackerel, herring, anchovy, and sardine) could help in reducing the frequency and intensity of headache attacks. A dietary intervention increasing omega-3 and reducing omega-6 fatty acids may reduce headache pain and improve quality-of-life.

Consumption of omega-3 fatty acids improves migraine symptoms, and lower intake of EPA and DHA has been associated with higher frequency of migraine attacks. Dietary supplementation with omega-3 associated with a pharmacological treatment is useful for the prevention of migraine attacks, reducing the frequency and intensity of headache attacks in more people suffering from migraine than medicine alone.



Soares AA, Louçana PM, Nasi EP et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2017 Jan 5:1-5. doi: 10.1080/1028415X.2016.1266133. [Epub ahead of print]


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