Psoriasis symptom severity reduced by Omega-3 fatty acids


Psoriasis is an inflammatory disease of the skin characterised by the formation of scales, leading to itching and pain. In Spain, it is calculated that over a million people suffer from the disease. Furthermore, it affects a growing number of people, as the proportion of patients with psoriasis in Spain in the last 15 years has risen from 1.4% to 2.3% today.

Trials for different nutritional strategies have been under way for some time to see whether anything can help alleviate the symptoms. And this has included the possible beneficial effect of omega-3 polyunsaturated fatty acids. Therefore, an article was recently published on this topic in the journal ‘Clinical Rheumatology’ in which investigators reviewed the results of 10 studies with a total of 560 participants to assess the efficacy of omega-3 supplements as a treatment for psoriasis.

Omega-3 would reduce the severity of symptoms according to studies

The authors describe its possible use depending on a number of different variables. One of the measures for assessing severity is the Psoriasis Area Severity Index (PASI), which combines different symptoms, such as erythema, desquamation, induration and the formation of calluses. The overall findings from the 10 studies, analysed jointly, indicate that omega-3 can reduce the PASI score. In other words: it reduces the severity of the symptoms. Enven more, the review also observed that supplements alleviate erythema, scale formation and itching.

The drugs available for treating the disease are increasingly effective, but as the authors note, ‘given the adverse effects associated with traditional therapies for psoriasis, it is essential that current, less harmful treatments are investigated’.

In this context, they add that ‘polyunsaturated fatty acids are among the most promising compounds for a safe supplementary treatment for many skin disorders, including psoriasis’.



Clark CCT, Taghizadeh M, Nahavandi M, Jafarnejad S. Efficacy of ω-3 supplementation in patients with psoriasis: a meta-analysis of randomized controlled trials. Clin Rheumatol. 2019 Feb 18. doi: 10.1007/s10067-019-04456-x.

Zuccotti E, Oliveri M, Girometta C, Ratto D, Di Iorio C, Occhinegro A, Rossi P. Nutritional strategies for psoriasis: current scientific evidence in clinical trials. Eur Rev Med Pharmacol Sci. 2018 Dec;22(23):8537-8551. doi: 10.26355/eurrev_201812_16554.