Nutrigenomics and omega-3 fatty acids

 
nutrigenomica y omega-3
 
 

Each cell in the human body contains about 25,000 to 35,000 genes. Genes carry the information that determines our traits; each gene has specific instructions for making proteins: a gene “tells” a cell how to make a specific protein (gene expression). This is very important because proteins are the building blocks for everything in our body (for example, muscles, bones, teeth, hair, and blood), and they are used by the cell to perform certain functions, to grow, and to survive. Each one of us has a different set of genes, and a person’s genes determine in part a person’s risk for certain diseases.
Nutrigenomics is the study of the link between nutrients (carbohydrates, protein, fat, vitamins, and minerals) and genes. The importance of nutrigenomics resides in the knowledge about the interactions between genes and their products with nutrients in the development of certain diseases. Dietary components can alter gene expression directly or indirectly, showing a beneficial or harmful physiological effect.
Besides their structural function in cell membranes, omega-3 long-chain fatty acids (for example, DHA and EPA) and their derivatives regulate key genes of metabolic processes (the organic processes that are necessary for life) within cells and tissues in the organism. Nowadays, scientists are intensively studying these mechanisms, with the objective of identify which ones are involved (at molecular level) in the beneficial effects of omega-3 fatty acids.
We will keep you informed.

Bibliography:

Rodríguez-Cruz M, Solís Serna D. Nutrigenomics of ω-3 fatty acids: Regulators of the master transcription factors. Nutrition. 2017;41:90-6. http://www.nutritionjrnl.com/article/S0899-9007(17)30089-8/fulltext